There are many treatment methods for hemangioma, including surgical resection, laser treatment, local injection drug treatment, oral drug treatment, copper needle treatment, minimally invasive interventional treatment, radiofrequency ablation treatment, radiation (isotope strontium 90) treatment and cryotherapy. Each treatment method has its own advantages and disadvantages and certain indications (not a certain method that is often advertised as the best and can cure all kinds of hemangiomas), and the most suitable treatment method must be selected objectively and dialectically depending on the different stages of development of vascular lesions, the type, size and location of vascular lesions, the patient’s age, health condition, and the presence of complications. Sometimes it is necessary to use a combination of treatment to obtain a more satisfactory treatment effect. Topical drug treatment: commonly used are Imiquimod and Thiamoxinan, but the effect of Imiquimod is better than Thiamoxinan, and Thiamoxinan has some effect on the heart, so there are more hospitals using Imiquimod. It’s not a good idea to use it for the treatment of hemangioma. Theoretically, it is a good treatment for hemangioma, but the shortcoming is that the effect is not very reliable, only 70% of the patients are effective. Wen Qiang, Department of Nuclear Medicine, China-Japan Friendship Hospital of Jilin University Local injection drug treatment: originated from the 1960s, the principle is to inject drugs into the tumor tissue of hemangioma, causing sterile inflammation, and local fibrotic reaction after the swelling disappears, which shrinks or occludes the hemangioma and blood vessel cavity. Injections are commonly used in three kinds, one, human metabolites, is the oldest hemangioma treatment drugs, mainly hormones, urea. Although they are human metabolites, hormones have the most side effects of all injectable drugs, while urea treatment has the most number of shots of all injectable drugs. The hormone is usually played once a month, usually a total of seven or eight times, and urea is played every day, a course of treatment for seven days in a row, and then every month for seven days, to play several courses, equivalent to a total of 20 to 30 times. But these two drugs also have the advantage that is the cheapest of all the drugs, whether it is hormones or urea, a drug is almost a dozen to a few dozen dollars. Second, chemotherapy drugs, once used by most hospitals as a replacement product for human metabolites, mainly Pingyangomycin, bleomycin. The effect is good, is the longest time with the most hospitals to play the drug, but is after all, is a chemotherapy drug, many people will be afraid, the price is medium, the cost of drugs plus injection fees, once three or four hundred, once a month to play is enough. Three, plant extracts, mainly polygamyl alcohol, polycadol. It was first discovered by German doctors and used in the treatment of hemangioma. It has the lowest risk and the best effect, but it is more expensive, one polygoniol costs 600, and once a month is enough. Laser treatment: originated in the 1990s, laser is a monochromatic light with high energy, precise focus and certain penetrating power. Unlike the radioactive treatment mentioned earlier, lasers are light in physical nature, not rays, and are not radioactive. There are many lasers used in medicine, but not all of them can be used to treat hemangioma, and only a few of them are specifically used to treat hemangioma. The treatment principle is to use oxygenated hemoglobin to selectively absorb light of specific wavelength, which causes instantaneous coagulation of hemoglobin in blood vessels, resulting in occlusion of vessel lumen and then degradation and disappearance, for the purpose of treating hemangioma. Early angioma lasers include VP laser, photodynamic laser and E light, while LP laser is the new laser. The VP laser (including KTP532, dye 585 and dye 595) is the first laser used for the treatment of hemangioma. Because of its short wavelength and pulse width, it is as effective as cryotherapy and radiation therapy for small superficial vascular lesions, but not for larger deep vascular lesions. The LP laser (1064nm laser) is a new laser that has been launched in the past two years. Compared with the VP laser, it has a longer wavelength and wider pulse width, and has a better effect on strawberry hemangioma, regardless of its size and depth, and also has a better effect on severe erythema and wine discoloration. Most hospitals still stay with the previous VP dye laser, which has been used for a long time and is familiar with it after all. Photodynamic laser therapy (also known as photosensitized laser therapy), the basic treatment principle is much the same, but on top of the laser treatment with a photosensitizer to increase the effectiveness of the laser. The photosensitizer is injected into the patient’s blood vessels first, and then a black light or long wavelength laser is used to irradiate the area of the hemangioma. The activation of the photosensitizer produces a photochemical reaction and causes photosensitive damage to the endothelium and interstitium of the hemangioma, which activates the endogenous coagulation system and causes intravascular coagulation and thrombosis, leading to further damage and destruction of the vessel wall and occlusion of the vessel lumen to achieve the treatment purpose. It is mainly used for the treatment of wine spots and nevus, but this treatment must be strictly protected from light during and one month after the treatment, otherwise serious photosensitivity reaction will occur, which is risky. E light, mainly used for the treatment of wine discoloration and bright red nevus, only uses E energy instead of photosensitizer to promote the absorption of light, so there is no need to avoid light. Radiation (isotope strontium 90) treatment: It is the commonly said pill dressing treatment, which originated from the 1970s, the most commonly used is isotope strontium 90 dressing, of course, there is also P32 colloid injection, and shallow X-ray direct irradiation, the common principle of its treatment is to use nuclear radiation rays generated by radioactive elements to bombard the nucleus of the tissue in the lesion area, so that the DNA strand and RNA strand in it are broken and the This causes cell death and disintegration due to the synthesis of nuclear proteins, resulting in radioactive damage at the treatment site to achieve the therapeutic effect. It can only be used for the treatment of strawberry hemangioma, and is mainly effective for minor superficial vascular lesions. Cryotherapy: Originating from the 1950s, it mainly uses the strong low temperature (-96℃) caused by the volatilization of liquid nitrogen to condense the skin, hemangioma and the tissues around the hemangioma in the lesion area, causing ice crystals to form in the cells and leading to cell rupture, disintegration and death to achieve therapeutic effects. It is only applicable to small superficial strawberry hemangioma, and the effect is not very reliable and has more side effects. Radiofrequency ablation therapy: This is the minimally invasive superconducting therapy that many private hospitals use to produce high-frequency electrocoagulation in the tumor by using radiofrequency current to act on the tumor, which directly acts on the tumor cell membrane and the elastic fibers and collagen fibers in the tissues around the blood vessels to emulsify, coagulate and contract the vessel wall, so that the tumor shrinks rapidly until it disappears and the deformed blood vessels lose the environment for re-expansion, thus achieving the therapeutic effect. This method can theoretically be used for the treatment of many kinds of hemangiomas, but clinical practice proves that it is mainly effective for hemangiomas with lymphatic components, and now it is mainly used for the treatment of lymphatic capillary hemangioma and multiple lymphatic-vascular-lipoma. For hemangiomas with mainly vascular components, the effect is not very good and the scars after treatment are obvious. Minimally invasive interventional treatment: It is a modern minimally invasive surgical procedure, which means that under the guidance of X-rays, an arteriovenous catheter is inserted from the root of the thigh and penetrates all the way to the site of the hemangioma, and then drugs are injected into the tumor through the catheter to produce sterile inflammation in order to achieve the effect of occlusion of the tumor vessels. Minimally invasive means less invasive than traditional surgical procedures. Most hospitals mainly use it for deep limb trapezoid hemangioma and visceral hemangioma, but when using interventional treatment, the indications should be strictly controlled and the flow of embolic agent into other organs should be avoided. Most superficial hemangiomas are simpler to treat with direct injections, and if only measured by the standard of minimally invasive, the injections can be considered non-invasive. Copper needle treatment: The principle is that after the copper needle is placed into the tumor, the electric charge causes the solid components of the blood to coagulate around the copper needle to induce thrombus formation, occluding the blood sinus and the blood vessels connected to the hemangioma, and the tumor subsides. It is mainly used for the treatment of cavernous hemangioma and vascular malformation. For cavernous hemangioma with multiple larger vessels communicating with it, copper needle retention treatment can be used. Surgery: It is a very early treatment method for hemangioma, but it is rarely used in hospitals or departments that have the conditions to carry out other hemangioma treatment methods nowadays. Generally speaking, because it is a hemangioma, the lesion area is rich in blood vessels and the blood volume is large, so the bleeding during the operation is extremely large, and the operation is difficult and dangerous. Therefore, surgical treatment should strictly grasp the indications and weigh the value of surgery before deciding whether to choose surgical treatment. Oral medication: The traditional oral medication is hormone, which may inhibit the abnormal proliferation of capillary endothelial cells of hemangioma, so that the proliferation process can be stopped as soon as possible to achieve the treatment of proliferating hemangioma, mainly for the treatment of hemangioma with a particularly wide area. The majority of the hospitals are catching up with the fashionable treatment of hemangioma with oral insulin. The main reason is that a French doctor in the treatment of heart disease inadvertently found that it also has a better effect on hemangioma, after the report, recently applied to the clinical application of hemangioma treatment, its treatment principle is unknown, and the indications for hormone therapy are the same, because everyone is afraid of hormones, so relatively speaking, insulin does not sound as scary as hormones, so now everyone is fashionable to eat this, but The effect of oral medication is really slow, and many of them take a long time, after all, there is certainly no benefit to taking too much of any medicine, so generally few hospitals use medication as the preferred treatment method, and generally it is mainly used to treat a wide range of hemangiomas, and other methods are not good. The main treatment method is to treat hemangioma that is particularly widespread and no other method works well. Although there are many treatment methods for hemangioma, any treatment actually has risks or side effects. If I purposely emphasize that there is any method that is the best without any risks or side effects, you should not believe me, even I myself do not believe that there is such a good method. In fact, as we all know, the most important thing to look at is to identify and treat the disease, so a reasonable plan is to choose a relatively appropriate treatment method according to the specific circumstances of the condition. The general principle is that if the hemangioma is mild, the most suitable treatment method should be chosen according to the condition. For complex and serious hemangioma, it would be better to use the combined treatment of multiple methods, so as to give full play to the comprehensive effect of each method, reduce the number of treatments and side effects as much as possible.