Smoking does not have a direct effect on gout, but gout patients still need to quit smoking. Because gout is a metabolic rheumatic disease, it is often combined with other metabolic diseases and cardiovascular diseases, such as hyperlipidemia, diabetes, hypertension, and coronary heart disease, and smoking has an effect on cardiovascular diseases. Although smoking does not have a direct effect on gout, it is necessary to quit smoking in order to reduce the impact on the disease, especially in patients with combined cardiovascular and cerebrovascular diseases. The main clinical manifestations of gout are sudden joint redness, swelling, heat and pain. As the disease progresses, patients will gradually develop chronic gouty arthritis, gouty nephropathy and other manifestations, and with the prolongation of the disease, cardiovascular and cerebrovascular diseases and other metabolic abnormalities can also appear.