Scleroderma is a connective tissue disease characterized by inflammation, degeneration, thickening and fibrosis of the skin leading to sclerosis and atrophy, which can cause multi-system damage. In addition to degenerative lesions of the skin, synovial membrane and finger (toe) arteries, internal organs such as the digestive tract, lungs, heart and kidneys can also be involved in systemic sclerosis. Roasted ephedra, rehmannia, white mustard seed, ginger, angelica, cinnamon stick, peach kernel, safflower, Chuanxiong, red peony, raw earth, danshen, qiangwu, stiff silkworm, etc. Tang Xianping, Department of Rheumatology and Immunology, Wangjing Hospital, Chinese Academy of Traditional Chinese Medicine, adds Qiang Wu, Dou Wu and Wei Ling Xian for joint pain. If the Raynaud’s phenomenon is obvious, add chicken blood vine, curcuma longa, and ginger yellow, etc. 1. Damp-heat stasis: Symptomatic features: local skin thickening or tension. The skin of the fingers is swollen and the skin lines disappear. Even ulceration and necrosis of the skin of the finger ends. With fever, joint swelling and pain. Red or dark red tongue, yellowish greasy coating, slippery pulse. Treatment: Clearing heat and relieving dampness, resolving blood stasis and promoting circulation. Radicals: Xuan Piao Tang combined with Si Miao Yong An Tang plus or minus. Radix Angelicae Sinensis, Radix et Rhizoma Ginseng, Radix et Rhizoma Polygonati, Radix Dioscorea Z, Radix Papaya, Radix Achyranthes Bidentatae, Semen Coix, Atractylodes Macrocephalae, Slippery Rock. Addition and subtraction: add antelope horn powder, white flower and snake tongue herb, cypress, forsythia, etc. if heat is heavy; add fu ling, antibiotics, carthamus, zedoary, etc. if swelling is very serious; add frankincense, myrrh, etc. if skin ulcer is painful. Chinese patent medicine: can use damp-heat paralysis punch and so on. 2.Phlegm stasis paralysis: Symptom characteristics: skin hardening and thickening, sensory loss. Swelling of joints. With dull facial expression, dizziness, heavy head, soreness and pain in the limbs, sallow face, nail fault, and even finger ulcers, and distension and fullness in the abdomen. The tongue is dark red or light dark, with white greasy coating and sunken or slow pulse. Treatment: Removing phlegm, eliminating blood stasis and promoting circulation. Remedy: Warming gall bladder soup combined with peach and red four-item soup plus reduction. Chen Pi, Poria, Radix et Rhizoma, Hovenia, Bamboo Roo, Calamus, Peach kernel, Safflower, Red peony, White peony, Chuanxiong, etc. Addition and subtraction: add Liu Yao Nuo, Fructus Fo Guang, Curcuma longa, San Leng, etc. in case of obvious stasis; add Bile Star, White Mustard Seed, Alligator Piper, etc. in case of heavy phlegm. Add Astragalus, Radix Codonopsis, etc. in case of Qi deficiency. Chinese medicine: Yi kidney rejuvenation pill, Dahuoluo pill, etc. can be used. 3.Qi stagnation and blood stasis: Symptom characteristics: skin hardening in a limited or generalized manner, or even atrophy. Mood swings or cold is the fingers turn white and purple. With anxious and irritable or depressed mood, irregular menstruation or menstrual abdominal pain or breast pain in women, poor appetite and swelling. Loose or dry stools. Dark red tongue, thin white fur, string pulse. Treatment: De-stressing the liver, nourishing blood and activating blood circulation. Radix Rehmanniae jasminoides combined with Siwu Tang plus or minus. Dampi, Gardenia, Chai Hu, Poria, Atractylodes, Angelica, White Peony, Red Peony, Radix et Rhizoma. Add and subtract: add gunnera, salvia, kombu, etc. if the finger turns white and purple. If the abdominal distension is obvious, add Citrus aurantium shells, thick park, Chen Pi, etc. Chinese patent medicine: can be used to add flavor prodigality san, prodigality pill, etc. 4.Yang deficiency and blood stasis: Symptom characteristics: including circumferential skin swelling and hardening, Raynaud’s phenomenon, swallowing difficulties, restricted opening, with joint pain, cold extremities, hoarseness, cough, hair loss, dull or purple tongue, thin white coating, sunken and astringent pulse. Treatment: Warming Yang, resolving blood stasis, activating blood circulation and promoting paralysis. Direction: Yang He Tang combined with Gui Bai Wei Ba Wei Wan plus reduction. Ephedra, Shu Di Huang, Cinnamon, Deer Antler Gum, White Mustard Seed, Ginger, Safflower, Chicken Blood Vine, Sliced Pith, Cornu Cervi Pantotrichum, Raw Yam, Danshen, Roasted Licorice, etc. Addition and subtraction: for Yang deficiency, add Xianmao, Epimedium, etc. For deficiency of qi and blood, add astragalus, henbane, angelica, etc. Traditional Chinese medicine: Guihuixiang Ba Wei Wan, Quan Lu Wan, etc. can be used.