Both belong to primary osteoporosis Postmenopausal osteoporosis called osteoporosis type I, postmenopausal women, around 50 years old, mainly due to endocrine changes in the body, due to the reduction of estrogen, the effect of estrogen on bone metabolism is mainly to promote the secretion of calcitonin, indirectly inhibit the function of osteoclasts and reduce bone resorption. Age-related osteoporosis, also known as osteoporosis type II, has an age of onset around 70 years old and can also occur in elderly women, mainly due to the aging and declining function of tissues and organs: 1. Declining function of osteoblasts in the elderly, reduced bone formation; declining function of the kidneys, reduced amount of 25(OH)D3 converted into 1,25(OH)D3 in the kidneys; affecting calcium absorption; 2. Declining function of the epithelial cells of the small intestine mucosa The formation of calcium-binding protein is insufficient, or its activity is reduced, which affects the absorption of calcium in the intestine; 3, the synthesis of a variety of proteins is reduced, which affects the formation of bone matrix. 4, the reduction of androgens is also a factor.