Syphilis is a type of sexually transmitted disease that is caused by infection with the syphilis spirochete. It is transmitted, firstly, through sexual contact, which is the most important way. There is also vertical transmission, which is from mother to fetus. Then there is the transmission by blood transfusion, and there are other ways of transmission that are very rare. The first thing to do is to take active treatment. The treatment method preferred penicillin treatment, in the early or late stage of the general to take benzathine penicillin intramuscular injection, once a week, treatment 3-4 times, after treatment can be three months to review once, this is the first year. This is the first year. The second year is reviewed once every six months, and the third year is reviewed once at the end of the year. If the titer decreases four times or more at each review, it means it is effective and can continue to be observed. If the titer does not decrease, but increases or decreases less than four times, it means that the treatment is ineffective or there is an infection.