As the years go by, everyone looks older. This is a natural law, yet youth is the eternal goal of beauty seekers. Over the past few decades, wrinkle rejuvenation has undergone many changes. In fact, people have been using surgical and physical methods for cosmetic treatments for a long time, such as ultrasonic atomized cold spray, medium frequency electrical stimulation, and infrared physical therapy. Later on, mechanical grinding and chemical peeling methods were mainly used for wrinkle removal surgery, etc. Often the damage is large. The efficacy of various drug treatments is not satisfactory, and some methods can make a definite improvement of the new epithelium, but the operation is complicated, and there are many postoperative side effects and risks. How to effectively and safely achieve skin rejuvenation (wrinkle rejuvenation) is a major problem in cosmetic surgery. Can we make the skin ten years younger and make life more colorful? In recent years intense light (IPL), radio frequency (RF), semiconductor laser, pigment laser, fractional laser, infrared tightening technology, etc. Non-surgical, minimally invasive techniques have been able to do just that. High-energy ultra-pulsed or scanning C02 laser resurfacing is a new technique recently pioneered in the field of cosmetic surgery, and its remarkable efficacy and high safety have made this technique popular among Caucasians, despite its efficacy, the post-operative inflammatory reaction is obvious, the erythema period is long, and the main disadvantage is that most Caucasians will have significant hyperpigmentation within 2-6 months after surgery [which is obviously different from Caucasians, who rarely The most important disadvantage is that most of the yellow patients will have significant hyperpigmentation within 2-6 months after surgery [unlike the white patients, who rarely have hyperpigmentation]. Therefore, it is difficult to promote the use of all these methods in China. Recently, several non-ablative non-destructive laser wrinkle rejuvenation devices have emerged, such as IPL, CoolTouch, SmoothBeam and NLite, which have very mild side effects after treatment and have certain clinical efficacy. The advantage of this new laser is that it improves the superficial skin aging of the face, but it is difficult to reach the deeper layers of the skin, especially the deep dermis. RF technology has evolved to combined electro-optical integrated technology, which is the fourth generation of skin rejuvenation technology emerged and developed to begin to be applied to the treatment of deeper tissues of the body. Fractional laser or fractional laser is a new type of laser technology after traditional laser, photon and RF technology, which has the advantages of rapid and significant effect of invasive treatment, and small side effects and short recovery time of non-invasive treatment. It is a qualitative leap and revolutionary progress in the history of skin rejuvenation treatment.