Spontaneous abortion is currently one of the common clinical evidence of gynecology, the incidence rate of 8%-10%, and in recent years there is an increasing trend. If the treatment of pre-eclampsia is not timely, recurrent spontaneous miscarriage often further develops into habitual miscarriage, which becomes one of the most difficult conditions to treat in infertility specialties. In addition to miscarriages due to chromosomal abnormalities and other embryonic causes that are difficult to treat, most of the miscarriages related to maternal factors can be treated to continue the pregnancy until normal delivery. For thousands of years, TCM has made great contributions to the reproduction of the Chinese nation, and has also accumulated rich experience in the treatment of miscarriage. According to Chinese medicine, the main cause of miscarriage is the weakness of the mother’s internal organs and the imbalance of qi and blood, resulting in the fetus not being fixed, especially related to the strength and weakness of kidney qi, the nourishment of the spleen and stomach, blood heat and blood stasis, etc. The kidney is the master of reproduction, and the woman’s kidney is tied to the fetus, and kidney qi is the true qi of the mother and the son. If the kidney is deficient, it cannot hold the fetus, the ancients said: where the fetus is hot, the blood is easy to move, and where the blood is moving, the fetus is restless. After pregnancy, the woman relies on qi to tie the fetus, blood to nourish the fetus, if the qi and blood are insufficient or out of balance, so that the fetus is displaced, the fetal element is not solid, then miscarriage occurs. Chinese medicine also says that the kidney is the essence of the first day, which is the main reproduction, and the spleen is the essence of the second day, which is the main biochemistry of qi and blood, so benefiting the kidney and strengthening the spleen is the basic method to calm the fetus, and the famous formula of Zhang Xichuan, a famous doctor in the Qing Dynasty, is the embodiment of this basic treatment. The formula includes Cuscuta sinensis to tonify the kidney and nourish the essence, benefit the yin and consolidate the yang; Sang Sang Sang and Sequoia to strengthen the kidney and waist and stop the pain; Agaricus to nourish the yin and nourish the blood and stop the bleeding; the four drugs, in strict combination, are not warm but not cold, tonifying but not stagnant, and the clinical practice often adds products that benefit the qi and strengthen the spleen, so that the successive heavens can be tonified together, the qi and blood can be generated and the fetal element can be consolidated. The purpose of preserving and nourishing the fetus is achieved. Even for miscarriages caused by other factors, this formula is often used as the basis for addition, subtraction and modification to achieve good results. It is because of the good clinical efficacy of Shou Fetal Pill for hundreds of years that it has aroused the interest of many modern scholars, and further research has been conducted on it by using modern technology. It is well known that superoxide dismutase (SOD) can resist the damage of free radicals. In addition, it has been found that SOD has a good protective effect against DNA damage induced by cyclophosphamide (chemotherapy drug), thus reducing the occurrence of teratogenesis. Based on these research bases, some scholars have obtained significant fetal preservation effects after treating two animal models of miscarriage caused by RU486 (anti-pregnancy drug) and hexestrol with Shou Fetal Pill, and found that Shou Fetal Pill can promote the development of uterus and ovaries in mouse pups, significantly inhibit the contraction frequency and activity of isolated uterine smooth muscle in normal and pregnant rats, and significantly counteract the oxytocin-induced strong contraction of isolated uterine smooth muscle in rats. The acute toxicity, long-term toxicity and reproductive toxicity tests all showed no significant toxic side effects of oral administration of Shou Fetal Pill to animals. The current study concluded that the fetus preservation effect of Shou Fetus Pill is the result of multi-factor and multi-mechanism synthesis, which both acts on the receptor and regulates the balance of sex hormones, fully reflecting the overall therapeutic effect of TCM. At present, the drugs such as Quick Pregnancy and Fetus Protection Spirit and Quick Effect Fetus Protection Spirit, which are popularly used by obstetricians and gynecologists in clinical practice, are made by adding flavor to Shou Fetal Pill as the basic formula. Of course, there are many causes of pre-eclampsia miscarriage, especially for patients who have had multiple miscarriages, preventive treatment should be carried out as early as possible, and Shou Fetal Pill is only one of the safe and effective formulas commonly used in Chinese medicine. And at the same time, we should pay attention to the regulation of life and living, moderate or even prohibit intercourse, avoid strenuous exercise and emotional fluctuations, because these can cause damage to the internal organs, disorder of qi and blood, fetal energy disturbed and affect the effect of treatment.