Ibuprofen extended-release capsules are over-the-counter drugs, which patients can buy and use in pharmacies by themselves. The incidence of side effects is low, mainly gastrointestinal reactions, but long-term application in large quantities can cause gastric bleeding, headache, tinnitus, vertigo and other central nervous system reports, and very few patients cause allergies. Specific summary is as follows: 1. The most common adverse reactions are gastrointestinal reactions, nausea, vomiting, abdominal pain, diarrhea, constipation, indigestion, long-term use causes gastrointestinal ulcers and bleeding. It is recommended to take this drug after meals. 2, headache, vertigo, tinnitus and other central nervous system reactions. 3, a very small number of patients appear rash, itching, urticaria, skin allergy, exfoliative dermatitis, erythema multiforme and skin necrolysis loosening and other allergic reactions, patients with allergic reactions should stop using the drug. Oral anti-allergic drugs can be used for treatment, serious symptoms require immediate medical attention. 4, very few patients have experienced cystitis, allergic nephritis, nephrotic syndrome, renal failure, therefore, severe renal insufficiency is prohibited. 5, edema, bronchospasm, asthma patients with allergy to aspirin is prohibited. 6, long-term high doses lead to blood disorders, liver damage, etc. In short, patients should have a scientific understanding of the side effects of this drug, pay attention when using it, and stop it immediately when the corresponding symptoms occur and seek medical attention. For specific medication, please refer to the clinical situation and the guidance of the physician.