Gout is a group of disorders of purine metabolism, characterized by hyperuricemia and the resulting recurrent episodes of gouty acute arthritis, gouty stone deposits, gouty stone chronic arthritis and joint deformities, often involving the kidneys to cause chronic interstitial nephritis and uric acid kidney stone formation. It is often associated with hyperlipidemia, obesity, diabetes, hypertension, atherosclerosis and coronary artery disease, and is a hereditary disease. It can be secondary to kidney disease, blood disorders and drugs. There are two sources of uric acid in the body: exogenous from the breakdown of nucleotides in nucleoprotein-rich foods; and endogenous from the synthesis of amino acids, ribose phosphate and other small molecules in the body and the metabolism of nucleic acids. For the development of hyperuricemia, endogenous metabolic disorders are more important than exogenous factors. It is important to avoid eating a high purine diet. For example, animal offal, bone marrow, seafood, clams and crabs are the richest in purines; fish and shrimp, meat, peas and spinach also contain a certain amount of purines; vegetables, fruits, milk and eggs do not contain purines. Obese patients must reduce the intake of calories. Drink more water to facilitate the excretion of uric acid. Avoid triggering factors such as overexertion, stress, alcohol consumption, cold, humidity and joint injury. Patients should rest in bed and elevate the affected limbs during acute attacks. The earlier the drug treatment, the better, and the drug can be used non-steroidal anti-inflammatory drugs. For increased uric acid, uric acid-lowering drugs or drugs to promote uric acid excretion are available.