Causes of high glutathione and glutathione aminotransferase

  Glutathione, also known as alanine aminotransferase, is widely distributed in the cytoplasm of various cells and is particularly concentrated in liver cells. When the cells containing high concentration of ALT are destroyed, the enzyme will be released into the blood, and the blood test will indicate an increase in ALT. The causes are seen in the following points: 1, strenuous exercise before the test, staying up late, poor rest, overwork, drinking alcohol, eating too greasy food, etc.; 2, hepatitis B, C and other viral hepatitis leading to liver damage; 3, biliary tract disease.  Glutamic aminotransferase, also known as aspartate aminotransferase, is mainly distributed in cardiac muscle cells, followed by skeletal muscle cells, liver cells and kidney cells. Because of the high concentration of glutathione in the above cells, glutathione will be released into the blood in large quantities after the destruction of the above cells, resulting in elevated serum glutathione levels. The causes are seen in the following: 1) heart disease, mainly myocardial infarction, which can cause a significant increase in glutathione; 2) diseases of the liver, such as acute viral hepatitis.  In addition, simultaneous elevation of glutathione and glutamic oxalacetic aminotransferase is most commonly associated with hepatocellular injury.