This is the most important topic of concern for outpatients. According to international guidelines, uric acid-lowering therapy should not be stopped and should be maintained for a long time. In my experience, after active uric acid treatment for about 1 year (depending on the patient’s condition and disease duration), most patients can be reduced to the minimum dose of maintenance medication; in fact, some patients can be maintained at a better blood uric acid level (only some patients) by exercise and diet and other lifestyle interventions after finally stopping the medication; while there are a few patients, uric acid will rebound when the medication is reduced, and these patients need These patients need long-term therapeutic dose maintenance.