Microwave ablation is a fast developing thermal ablation technique for tumor treatment in the last decade or so. It has the advantages common to thermal ablation techniques, such as easy to operate, less invasive, reproducible and can achieve complete local necrosis. For liver cancer patients, especially large liver cancer, microwave ablation is a good method, with 8-10 minutes per ablation, time period and less pain. Compared with radiofrequency ablation, microwave ablation also has the characteristics of fast warming speed, strong coagulation ability, less influence by blood flow factors, multiple antennas acting simultaneously, larger and stable coagulation range, etc. It has become a highly promising and promising treatment tool in thermal ablation therapy. The Department of Interventional Oncology of Beijing Ditan Hospital has been carrying out microwave ablation of liver cancer for 4 years, with more than 300 cases per year, and has rich experience, especially for patients with poor liver function and special location of liver cancer.