”Venous sinus thrombosis” is a rare disease commonly known as benign cranial hypertension or pseudotumor. The clinical manifestations mainly include recurrent headaches and eye swelling, mostly heavy in the early morning, and often misdiagnosed as neurological headache or neurasthenia. It is often easily overlooked in general brain CT and MRI examinations. Pathogenesis and mechanism: widespread or local thrombosis of intracranial venous system caused by infection, immune reaction, rapid change of progesterone level and abnormal increase of blood viscosity caused by various reasons, which obstructs cerebral blood circulation in venous phase and causes stagnation of venous blood in brain tissue, which may lead to brain swelling and cerebral hemorrhage; high and prolonged intracranial pressure will cause vision loss, and serious condition may lead to hemiplegia, blindness and even Death. The mortality rate is as high as 82%. Simply put, the “outlet” of the brain’s blood circulation is blocked by blood clots, resulting in increased venous pressure and intracranial hypertension, with the possibility of brain herniation. The death threatened Mr. Liu step by step, and the patient’s headache was slow and persistent, with progressive aggravation. Jiang Linfang, director of the Department of Neurology, saw the patient and was in a hurry, and treatment could not be delayed! The interventional department was immediately dialed to start the green channel for stroke. According to Niu Qingliang, the director of the imaging center, the speed of blood flow in the blood vessels is reflected in the image on the MRI film is different: the blood in normal people’s blood vessels, because of the fast flow speed, can not receive the signal from the MRI, so the filmed lumen shows a black shadow, according to this, we can think that Mr. Liu “blood vessel flow empty” phenomenon disappeared, it is likely to be a venous thrombosis. It is likely to be a venous thrombosis. The interventionalist made a needle hole in each of the patient’s thighs, and entered the femoral vein and femoral artery. The microcatheter was guided by a hair-thick guidewire to gradually enter the intracranial vessels, and then performed arterial and venous angiography. Normally the contrast agent enters the vessels and takes only 4C6 seconds to diffuse into the major blood vessels in the brain, but this time it was surprisingly slow, with no trace the closer it got to the exit. “The delayed emptying of the contrast agent meant that the blood did not flow at all.” A venous angiogram further confirmed the “total venous sinus thrombosis” and the results greatly exceeded the doctor’s expectations. The severity of the lesion was rare, which meant that the venous blood in the brain was not flowing at all. With the extension of time, the threat of death was increasing, and if not treated in time, the consequences were unthinkable! The surgery started at 6 pm and lasted for 6 hours until 1 am. With the assistance of angiography machine, the microcatheter entered the embolism site smoothly, and the guide wire was used to “break the embolism” and injected the thrombolytic drug urokinase. 。。。。 was opened on the right side. What about the left side? The left intracranial venous sinus was accessed via the superior vena cava through the left cephalic arm vein port super selectively. During the operation, Mr. Liu experienced the test of life and death. As the operation proceeded, the patient’s headache disappeared quickly and unconsciously the headache-suffering Mr. Liu entered a sweet sleep. Cerebral venous sinus thrombosis can be divided into local thrombosis and diffuse (multiple) thrombosis, for the former there are several reports at home and abroad, treatment can be systemic anticoagulation, surgical dissection of the diseased venous sinus thrombosis, or intravascular expansion of the occluded venous sinus and stent placement; in order to obtain the purpose of venous sinus recanalization. The treatment of diffuse venous sinus thrombosis has not yet been reported. Due to the extent of the lesion involving multiple venous sinuses, it is clearly impossible to rely on surgical procedures and local stenting and simple anticoagulation. With the development of intervention, “endovascular treatment” has greatly shortened the time to dissolve the thrombus and improved the efficiency to open the occluded venous sinus and restore the normal cerebral circulation. Especially in the absence of effective treatment for diffuse venous sinus thrombosis and cerebral venous thrombosis at home and abroad, the success of this procedure marks the leading position of our hospital in interventional medicine in China.