Thyroid nodules are most commonly benign nodules. If surgical removal under local anesthesia or partial excision of the gland is chosen, the cost should be around $2,000 for a single-patient limited disease in a level 1 hospital. If the nodule is multiple and requires a subtotal or partial excision of the thyroid gland, the cost will increase. Surgical treatment in a tertiary care hospital usually requires general anesthesia and intraoperative cryopathology is also required. So the cost will increase and relatively need to be doubled. In the case of thyroid nodules, if the lesion is malignant, a total excision of the gland is required. Lymph node dissection of the neck is also required, and the cost of the procedure increases. The most common cause of thyroid nodules is compensatory hyperplasia of the thyroid follicles. It is a benign disease, and there is some geographical variation in the causes.