Gout is a crystal-related arthritis caused by hyperuricemia, mainly because long-term hyperuricemia is not effectively controlled, resulting in the deposition of uric acid crystals around the joints and causing a sterile inflammation of the joints. The acute attack of gout is characterized by rapid onset, clear causes, self-limitation, easy recurrence, and single joint onset, as follows: First, rapid onset: generally within a few hours, redness, swelling, heat, pain, and dysfunction of the affected joints can appear, usually at midnight or early in the morning. Second, clear cause: often there is a clear cause, usually in the case of drinking alcohol or eating high purine food. Third, self-limiting: many first attacks can resolve on their own within a few days to two weeks. Fourth, easy to recur: easy to recur, and some patients have a family history. Fifth, single key onset: more common is a single arthritis, the best site is the first metatarsophalangeal joint.