Hepatocellular carcinoma is one of the common malignant tumors with insidious symptoms. When patients have conscious symptoms, they are mostly in the middle and late stages, and most of them have lost the opportunity of surgery at that time. The most effective treatment for patients with mid-to-late stage liver cancer is interventional therapy, including hepatic artery chemoembolization (TACE), anhydrous alcohol ablation, radiofrequency ablation (RFA), microwave ablation (MVCT), argon helium knife cryoablation and so on. The advantages of minimally invasive interventional therapy are less invasive, precise efficacy, fast recovery and low cost, which have become the standard treatment for mid- to late-stage liver cancer recognized at home and abroad. Ablation therapy is considered to be the treatment modality of choice for resectable hepatocellular carcinoma alongside with surgery.