The term peripheral vascular signs refers to changes in the pulsation or waveform of blood vessels that are found on examination of peripheral blood vessels in certain disease conditions. The causes of altered vascular pulsations or waveforms include hypertensive heart disease, obstructive hypertrophic cardiomyopathy, and hyperthyroidism. 1, hypertensive heart disease Hypertensive heart disease patients with heart failure may have alternating pulses present. The diagnosis of this disease is not difficult. The patient has a long history of hypertension. The patient has a long history of hypertension, and on examination, the apical pulsation is shifted to the left, with elevated pulsation, and the heart border is enlarged to the left. The electrocardiogram shows left ventricular hypertrophy and strain. Echocardiography may reveal enlarged left, active ventricle, thickened ventricular wall, and sometimes relative mitral valve closure insufficiency. It is worth noting that due to the presence of heart failure, the patient’s blood pressure can also be no significant increase, at this time, the diagnosis of the disease can be combined with the medical history and the above-mentioned tests to avoid misdiagnosis and delay. 2, obstructive hypertrophic cardiomyopathy obstructive hypertrophic cardiomyopathy used to be often called idiopathic hypertrophic subaortic stenosis, the main lesion is located in the lower part of the aortic valve septum, showing significant hypertrophy. The etiology of this disease is not very clear, but about 1 has a clear family history, so it is thought to be related to genetics, as an autosomal dominant disease, and some believe that it is related to abnormal catecholamine metabolism, hypertension, high-intensity exercise and other factors. The characteristic symptoms are syncope and chest pain, and the systolic murmur can be heard in the apical part of the heart, and the systolic murmur between the 3rd and 4th ribs at the left edge of the sternum is louder and rougher. The electrocardiogram showed left ventricular hypertrophy with pathological Q waves in II, III, aVF, aVL or V4 and V5. Echocardiography is of great importance in the diagnosis of this disease and may show a hundred symmetrical hypertrophy of the septal area with its outflow tract part protruding into the left ventricle. The peripheral vascular sign of obstructive hypertrophic cardiomyopathy is a heavy pulsatile pulse with a bimodal carotid wave. The diagnosis of this disease depends on echocardiography. In addition, cardiac catheterization may show a pressure difference between the left ventricular cavity and the outflow tract with a value greater than 2.66 kPa, as well as a positive Brockenbrough phenomenon (i.e., in the presence of a fully compensated intermittent ventricular premature beat, the intraventricular pressure increases after the premature beat, but at the same time the obstruction is increased due to increased contractility, so the intra-aortic pressure The intra-aortic pressure is reduced because of the increase in systolic force and the increase in obstruction, which is also important for the diagnosis of this disease. 3, hyperthyroidism Patients with hyperthyroidism can have peripheral vascular signs such as flooding pulse, water rushing pulse and capillary pulsation signs due to increased pulse pressure, especially in patients with hyperthyroid heart disease, in addition to the above peripheral vascular signs, symptoms such as chest tightness, palpitation and shortness of breath can also be seen. It can be easily confused with other heart diseases that cause increased pulse pressure. The difference is that the thyroid gland is enlarged to varying degrees in this patient, and there are signs of hypermetabolism, such as fear of heat, excessive sweating, weight loss, overeating, etc., as well as a series of manifestations such as increased serum T3, T4 and anti-T3, so the diagnosis is not difficult to determine.