The husband’s semen is specially treated to remove the dead sperm, impurities, anti-sperm antibodies and other components that affect conception, and at the same time improve the vitality of sperm, extract good quality sperm to meet the standard of fertilization, and inject it into the uterine cavity or cervical canal of the woman during ovulation to shorten the path of sperm to the fallopian tube and achieve a method to help conception. For the following cases, husband sperm can be considered for insemination: 1. The male partner is infertile due to low sperm (density <20×106/ml), weak sperm (viability <50% or grade A <25%), abnormal liquefaction (>30 minutes), sexual dysfunction (such as impotence, premature ejaculation, in vivo ejaculation disorder, etc.), genital malformation (hypospadias), etc. 2, female party due to abnormal cervical mucus secretion (severe cervicitis, after cervical surgery, too thick and too little cervical mucus, containing anti-sperm antibodies, etc.), genital tract abnormalities and psychological factors leading to infertility such as sexual intercourse can not. 3. Immunological infertility: one or both men and women have positive anti-sperm antibodies, etc. 4.Unexplained infertility: both parties have been infertile for many years without obvious abnormalities in the examination. 5. Age of both spouses (>35 years old), declining fertility, and failure to conceive after repeated instructions for intercourse.