Syphilis 1.32 refers to a syphilis serum titer test result of 1:32, and the time to turn negative after three injections varies from person to person. Syphilis titer 1:32 is already a strong positive, indicating that it is infectious. If you use benzathine penicillin G, you need to inject it once a week and use 3 shots for a course of treatment; if you use other drugs, you even need to increase the course of treatment. However, there is no definite time to turn negative, it depends on the patient’s specific condition, personal immune status, use of drugs, etc. A few patients can turn negative in 6-9 months, some patients have no significant decrease in virus titer in 12 months, or even 2 years still have not turned negative. After treatment, syphilis patients need to insist on at least 3 years of review, once every 3 months in the first year; once every 6 months in the second year; and once again at the end of the third year to help determine the efficacy of treatment and whether it is cured and whether it is recurring.