Why can’t patients with severe liver disease have a high protein diet?

  The liver is a very important digestive organ of the body, responsible for metabolism, synthesis, detoxification, excretion and other important functions of the body. When the liver is diseased and its function is significantly impaired, the body’s metabolic wastes will accumulate in large quantities, causing the body to develop “toxic” symptoms, and in severe cases, the body will become unconscious, which is called hepatic coma (also known as hepatic encephalopathy). The most important toxic substance that causes hepatic coma is called “ammonia”.  There are two main sources of ammonia in the body, one is from the body’s own proteolytic metabolism, which is endogenous and difficult to artificially control; the second is from the absorption of ammonia in the intestine, which is exogenous, and the amount of ammonia in the intestine is largely related to the amount of protein consumed, the more protein consumed, the more ammonia production in the intestine.  Ammonia is a harmful substance that can reach the brain with the blood and affect the function of brain cells, causing disorders in human thinking, abnormal behavior, and disorders of consciousness. Under normal circumstances excess ammonia in the body is removed by the liver by converting it into other substances that are not harmful to the body.  If the liver is severely damaged and loses its ability to remove ammonia, ammonia will gradually accumulate in the body, and when it reaches a certain level, ammonia poisoning symptoms will occur, the most intuitive manifestation of which is liver coma. With a high protein diet, the level of ammonia in the body is bound to rise sharply, and the end is not difficult to predict.  Therefore, for patients with liver disease, the doctor’s medication is important, but self-care awareness should be more important than medication, as the saying goes, “three parts treatment, seven parts nourishment”.  Diet is a very important aspect of self-care, and the essentials of diet are different for different diseases and conditions.  For patients with mild liver disease, we advocate a high-protein, high-vitamin, low-fat diet, with little or no spicy food, and a balanced and moderate diet. Eggs, milk, fish, shrimp, lean meat and various soy products are all high protein foods, while fresh vegetables and fruits contain a large amount of vitamin C and are high vitamin foods, only when consumed, we should pay attention to washing the pesticides left on the surface of vegetables and fruits to avoid new damage to the liver caused by pesticides. A diet high in protein and vitamins provides the body with the necessary nutritional elements to facilitate the repair of diseased liver cells.  Fatty meats and fried foods are high-fat foods that are not easily digested and should be avoided by patients with liver disease to avoid the accumulation of fat in the liver to form a fatty liver and aggravate liver damage.  For patients with moderate to severe liver disease, a light diet should be the mainstay, i.e. fine rice and noodles, supplemented by fresh vegetables and fruits, no high-fat and high-protein foods, and stir-fry with vegetable oils (such as peanut oil, soybean oil and tea oil) as much as possible, with little or no animal oils (such as lard). Patients with cirrhosis must also be careful not to consume hard or coarse foods (e.g., doughnuts, pot pies, walnuts, peanuts) that may cause bleeding from ruptured varices in the esophageal veins.  For patients with liver failure, it is especially important to restrict a high-protein diet, the purpose of which is to reduce the production and absorption of intestinal ammonia and avoid the occurrence of hepatic coma. Patients should also keep their bowels open, preferably once a day, to reduce the retention and accumulation of ammonia in the intestinal tract.  If there is no diabetes, patients can be encouraged to eat bananas, which provide nutrition and also have a laxative effect. In the hospital we often see that many people take eggs and milk to visit patients with severe liver disease, in fact, this is inappropriate, if it is more appropriate to take a couple of pounds of bananas.