Osteoporosis is a systemic bone disease characterized by a decrease in bone mass and degeneration of the microstructure of bone tissue (thinning, fracture and reduction in the number of cancellous bone trabeculae; porous and thinning of cortical bone), resulting in increased bone fragility and increased risk of fracture. The main clinical manifestations of osteoporosis are pain, shortening of height, hunchback, fractures and respiratory disorders. Among them, osteoporotic pain is the most common and main clinical symptom, accounting for about 58% of clinical symptoms, of which low back pain accounts for 70%-80%, mostly dull pain, no fixed pressure point, and spreads to both sides of the spine; the older the age, the higher the incidence, women’s symptoms are heavier than men’s, women’s symptoms are heavier after menopause than before menopause, pain is aggravated by sitting and standing for a long time, pain is relieved when lying down, late at night and early in the morning when waking up The pain is relieved when lying down, late at night and early in the morning when waking up. According to the statistics, 67% of osteoporosis patients have limited low back pain, 9% have low back pain with radiating pain in the extremities, 10% have low back pain with band pain, 4% have low back pain with numbness, and 10% have not only low back pain but also numbness in the extremities and intercostal neuralgia and weakness when flexing and extending the low back. Osteoporotic pain is manifested as generalized bone pain, and in severe cases, it is impossible to sleep. Treatment with calcitonin and other preparations can effectively relieve the pain. When a vertebral fracture occurs in severe osteoporosis, the vertebral compression and deformation is serious and the vertebral height is lost more, which can cause the intervertebral foramen to narrow and compress the nerve roots causing numbness and weakness in the lower limbs and sensory-motor dysfunction, which can be easily mistaken for the cause of intervertebral disc; or the compression of the thoracic spinal nerve roots caused by high intervertebral foramen causes pain and discomfort in the chest wall and other corresponding neurological symptoms, similar to angina pectoris, and upper abdominal pain similar to acute abdomen, combined with It is easy to misdiagnose when coronary artery disease is combined.