Most headaches from altitude reactions are caused by lack of oxygen to the brain, but they may also be caused by high blood pressure or alcohol consumption. Most of the patients may suffer from brain hypoxia after arriving at the plateau because of the low oxygen content, and severe brain hypoxia may cause hypoxic encephalopathy, which may cause headache, nausea, vomiting, memory loss and concentration problems. If the patient has severe brain hypoxia, oxygen therapy should be given promptly, which may also be caused by hypertension. If to the plateau may cause elevated blood pressure, severe elevated blood pressure can cause hypertensive encephalopathy, hypertensive encephalopathy patients may also have headache, nausea, vomiting, should be given timely blood pressure lowering treatment, if necessary, can lower the cranial pressure treatment. Commonly used blood pressure lowering drugs mainly include levamlodipine, amlodipine benzoate and irbesartan. The medication for lowering cranial pressure should be mannitol and glycerol fructose. In addition, if you drink alcohol after going to the plateau, it is easy to cause brain hypoxia.