If a patient has symptoms of high intraocular pressure (IOP) and headache, it is clinically recommended that the patient should be treated immediately with IOP-lowering medications, because in this case it is considered that the patient may have glaucoma. Glaucoma is a clinically important blinding eye disease. Glaucoma is a disease in which patients develop pathologically elevated intraocular pressure accompanied by visual field defects and optic nerve damage. When a patient has elevated IOP, it can lead to headaches. Therefore, once a patient has these symptoms, symptomatic treatment to lower the pressure should be given immediately. In general, depending on the patient’s condition, mannitol can be used systemically and topical IOP-lowering medications such as betagen eye drops and trichothecene eye drops can be used. The patient’s systemic status should be taken into account during treatment, and the patient’s condition should be carefully examined after the IOP has been stabilized, and laser or surgical treatment may be considered depending on the patient’s condition.