Persistent HPV infection is one of the causes of cervical cancer, but there is no unified concept of “persistent” worldwide, and it is generally believed that persistence should be at least two years before it can be called persistent. It should be noted that since there are multiple types of high-risk HPV in clinical practice, persistent infection should be a continuous infection of the same type. If one year the test is type 16 infection, the next year the test is negative for type 16, but it is type 18 infection, and the year after that the test is negative for type 18, but it is type 52 infection, then it is not a true persistent infection.