Hyperuricemia is a metabolic disorder caused by an impairment of purine metabolism. Clinically, it is divided into two categories: primary and secondary, the former mostly caused by congenital abnormalities of purine metabolism, the latter caused by certain systemic diseases or drugs. The saturation and concentration of uric acid in the body at 37°C is about 420 μmol/L (7 mg/dl), above which hyperuricemia is considered, and long-term hyperuricemia may lead to gout. Its treatment includes the following aspects: The pharmacological treatment of primary hyperuricemia and gout mainly includes It mainly includes: drugs to promote uric acid excretion such as benzbromarone, drugs to inhibit uric acid production such as allopurinol and febuxostat, alkaline drugs such as sodium bicarbonate, new uric acid-lowering drugs such as selective uric acid reabsorption inhibitors, etc. 2. Treatment of acute gouty arthritis: hyperuricemia is the basis for the development of gouty arthritis. Colchicine, non-steroidal anti-inflammatory drugs and glucocorticoids are the first-line drugs for the treatment of acute gouty arthritis and should be used early. Management of interictal and chronic gout attacks: For patients with frequent attacks of acute gouty arthritis, chronic gouty arthritis or gout stones, uric acid-lowering therapy should be performed. Treatment principles for secondary hyperuricemia: actively treat the primary disease; avoid or minimize the use of drugs and methods that may trigger and/or aggravate hyperuricemia; control the acute gouty arthritis attack as soon as possible. In addition, hyperuricemia and gout are often associated with metabolic syndrome, and should be actively treated with a combination of antihypertensive, lipid-lowering, weight reduction and improvement of insulin resistance. The main aspects of drug treatment for high uric acid are mentioned above, but the specific drugs used should be selected according to the cause and condition of the patient, and in addition to drug treatment should also pay attention to low purine diet and healthy lifestyle, so as to achieve better treatment results.