Varicocele is one of the common causes of low fertility in men, with a higher incidence on the left than on the right. Due to local blood flow obstruction, temperature increase and accumulation of toxic substances, it affects sperm formation and causes spermatogenic disorders, low sperm motility, oligospermia or azoospermia, etc. 2.Cryptorchidism Bilateral cryptorchidism can cause azoospermia. The chance of cryptorchidism becoming malignant is high, so early surgery is necessary. The possibility of treatment for this condition is very small. 3.Vas deferens obstruction is manifested as azoospermia or oligospermia. Most of them are found in the epididymis, and the efficiency of clinical treatment is 5%. 4.Bacterial infection Such infections caused by epididymitis, prostatitis, vasovaginitis, etc. can lead to sperm production disorders or semen abnormalities. 5, mycoplasma infections Mycoplasma ureaplasma is an important pathogen that causes non-bacterial urethritis. It can adsorb to sperm, increase the weight of sperm, impede the movement of sperm, or produce an enzyme-like substance that interferes with sperm-egg binding. Therefore, mycoplasma infection is a cause of male infertility. 6, Chlamydia infection Chlamydia infection is designated as a sexually transmitted disease (STD). In men, it mainly causes urethritis, which becomes chronic and worsens periodically, and can be combined with epididymitis, proctitis, etc. 7. Genetic factors and treatment Infertility caused by chromosomal abnormalities is usually incurable. If the female partner is normal, the application of assisted reproductive technology donor artificial insemination (AID) can be considered to achieve the goal of fertility. Thus, there is no point to check or not, and can be taken to hold the way to comfort. 8, endocrine factors hypothyroidism, congenital adrenal hyperplasia, etc., can affect the gonadal axis and cause spermatogenic disorders, severe hypogonadotropic disorders can cause sexual infantilism, pituitary insufficiency, hyperprolactinemia, etc., and can be accompanied by secondary impotence. Any kind of treatment needs to be repeated after 3 months for semen analysis to evaluate the efficacy. For patients who fail, only artificial insemination is recommended for other spermatozoa. 9, immune factors in the last two years, the literature shows that about 5-10% of couples with unexplained infertility may be caused by sperm antibodies. Sperm antibodies in the serum, especially sperm braking antibodies is a test item that must be screened for infertility. Sperm antibodies inhibit sperm capacitation and acrosome reaction, interfere with sperm upward movement, block sperm passage through the zona pellucida, interfere with sperm-egg union, and affect fertilized eggs, preembryos and implantation, causing immune infertility. Immune infertility is not common in infertile couples, and for technical reasons antibody tests are not accurate enough to confirm the diagnosis, and its treatment is in the experimental stage. These factors also affect the prostate, sexual function, etc. The psychological factors are also an important factor that seriously affect the efficacy of the male disease. The clinical efficacy of Chinese medicine in treating men’s diseases has attracted a lot of attention from the medical community at home and abroad in recent years, and the prospects for development are relatively broad. My personal experience shows that: in the treatment of male diseases, after more than thirty years of unremitting clinical exploration, in male infertility, chronic prostatitis, sexual dysfunction, orchitis, epididymitis …… and other male diseases treatment has a wealth of experience, while on the basis of this continuous learning, to learn from the experience. In order to have a greater breakthrough in the treatment of these diseases. More and better services for the majority of friends.