The pathogenesis of cerebral atrophy has not yet been elucidated, and although there is a lack of effective therapeutic measures, the following treatment methods can be used to improve symptoms and slow down the progression of the disease: 1, drug therapy: it is the most widely used treatment method. In addition, antidepressant or anxiolytic drugs can be added to improve patients’ mental symptoms such as anxiety, depression and apathy. 2, neurotrophic factor, stem cell therapy: neurotrophic factor has the function of promoting the repair and regeneration of damaged nerve cells, and some studies have shown that intravenous injection of neurotrophic factor can improve the symptoms of patients with cerebral atrophy. Another study shows that autologous stem cell transplantation can improve the clinical symptoms of patients with cerebral atrophy and restore their brain function to a certain extent, but this therapy is still in the research stage and has limited clinical application. 3, Chinese medicine, traditional Chinese medicine therapy: for some patients with cerebral atrophy in Chinese medicine based on the identification of evidence, blood circulation, blood nourishment, nourishing qi and marrow and other tonics can be used to a certain extent on the patient’s symptoms, delaying the progress of the disease. 4, behavior therapy: for patients with cerebral atrophy should encourage patients to try to maintain the ability to live, participate in social activities, strengthen rehabilitation treatment and training, adhere to follow-up visits, timely adjustment of treatment plans. In summary, cerebral atrophy currently lacks effective therapeutic measures, but can still improve the patient’s symptoms and slow down the progression of the disease, patients and their families should establish confidence in the treatment, comprehensive strengthening of protection, control the disease.