The pathogenesis of cerebral atrophy has not yet been elucidated, and although there is a lack of effective therapeutic measures, clinical symptoms can still be improved and disease progression can be delayed by some therapeutic means, mainly the following treatments: 1. In addition, cholinesterase inhibitors such as donepezil and carbaplatin can be added to increase the concentration of acetylcholine in the brain, or excitatory amino acid receptor antagonists such as meperidine can be applied to improve memory and cognitive function; in addition, antidepressant or anxiolytic drugs can be added to improve patients’ anxiety, depression, apathy and other mental symptoms. 2, neurotrophic factor, stem cell therapy: neurotrophic factor has the function of promoting the repair and regeneration of damaged nerve cells, and some studies have shown that intravenous injection of neurotrophic factor can improve the symptoms of patients with cerebral atrophy. Another study shows that autologous stem cell transplantation can improve the clinical symptoms of patients with cerebral atrophy and restore their brain function to a certain extent, but this therapy is still in the research stage and has limited clinical application. 3, Chinese medicine, traditional Chinese medicine therapy: for some patients with cerebral atrophy in Chinese medicine based on the identification of evidence, blood circulation, blood nourishment, nourishing qi and marrow and other tonics can be used to a certain extent on the patient’s symptoms, delaying the progress of the disease. 4, behavioral therapy: for patients with cerebral atrophy should encourage patients to try to maintain their ability to live, participate in social activities, strengthen rehabilitation treatment and training, train the brain, strengthen memory training, adhere to follow-up visits, timely adjustment of treatment plans. In summary, cerebral atrophy still lacks absolutely effective therapeutic measures, but it is not incurable and can still be treated by certain means to improve clinical symptoms and slow down disease progression.