China is a big drinking country, no matter in daily life or on New Year’s Eve, many people are “not drunk, not home”, which is very bad. In fact, drinking alcohol in moderation on a daily basis is generally not harmful; however, if too much is consumed, it can cause serious harm. The following is some knowledge of excessive drinking: according to the amount of alcohol consumed, differences in alcohol concentration, individual tolerance, etc., there can be different clinical manifestations: 1, light (simple intoxication): generally only emotional? The neurological manifestations of the state of verbal excitement, such as incoherent speech but not aggressive behavior, able to walk but with mild motor incoordination, drowsiness can be awakened, simple replies are basically correct, and normal neurological reflexes exist? 2.Moderate: any of the following can be present: 1) in a drowsy or comatose state 2) with manic or aggressive behavior that cannot be relieved by language or psychological diversion 3) severe ataxia with confusion and reduced neurological reflexes 4) with delusional hallucinations or convulsive episodes 5) blood biochemical tests with one of the following manifestations of metabolic disorders such as acidosis? Hypokalemia? Hypoglycemia; (6) The manifestation of obvious impairment of organ function on the basis of mild intoxication, such as arrhythmia related to alcoholism (frequent premature beats? Atrial fibrillation or atrial flutter, etc.), myocardial damage manifestations (ST-T abnormalities? Myocardial enzymology more than 2-fold elevation) or upper gastrointestinal bleeding? Pancreatitis, etc.? 3.Severe: any of the following may occur: 1) in a state of severe coma 2) microcirculatory perfusion deficit, such as pallor, cold skin, purple lips, rapid heartbeat, weak or non-palpable pulse, compensatory increase or decrease in blood pressure (below 90/60 mmHg or systolic blood pressure decreased by more than 30 mmHg compared to the basal blood pressure), coma with clinical manifestations of loss of compensatory phase of shock is also 3) Severe manifestations of metabolic disorders such as acidosis (pH ≤ 7.2)? Hypokalemia (serum potassium ≤ 2.5 mmol/L)? Hypoglycemia (blood glucose ≤ 2.5mmol/L); 4) Acute insufficiency of important organs such as heart, liver, kidney, lung, etc.? At this time, the diagnosis can be highly assisted by testing the concentration of ethanol in blood. However, because the absorption and clearance rates of alcohol vary individually and depend on many factors.