Drunkenness, which is actually acute alcohol poisoning, is a state of excitation or inhibition of the central nervous system caused by taking an excessive amount of alcohol. The mucous membrane of the oral cavity and the walls of the stomach and intestines have the ability to absorb alcohol. Alcohol into the mouth, the first by the oral mucosa absorption. If the oral cavity has a disease, the ability to absorb alcohol may increase, but the number is still very small. A large amount of alcohol is absorbed by the stomach and intestinal walls. The stomach absorbs about 25% and the intestines 75%. Therefore, the stomach and intestines, especially the small intestine, are the main channels for alcohol. After alcohol is absorbed, it enters the liver through the portal vein and later penetrates evenly into the internal organs and tissues through the bloodstream. In addition, when passing through the mouth trace alcohol: heat vaporization by the trachea, lungs into the blood for systemic circulation. Alcohol enters the body quite quickly. When drinking on an empty stomach, the first hour can be absorbed 60%, an hour later, can be as high as 90% or more. And alcohol gasification and excretion in the body is slow, so a large amount of alcohol accumulates in the blood or tissues. Alcohol itself has inhibitory and toxic effects on the central nervous system, respiratory center, heart and liver functions. It acts first on the brain stem reticularis. In normal times, the upwardly mobile reticular inhibitory system inhibits the cerebral cortex. As the reticular body is paralyzed by the sprinkling of alcohol, resulting in the hyperfunction of the cerebral cortex, the person appears to be active, love to nag, and even due to the excitement of becoming irritable and brash, not being able to control their own language and actions, which is usually said to appear intoxicated. When the concentration of alcohol in the brain increases to a certain amount, the cerebral cortex produces the consciousness of sleeping. Finally, a numb coma occurs, and the whole process can be divided into: excitation period, ataxia period, and lethargy period. If the concentration of alcohol per hectoliter of blood exceeds 600mg, it may lead to death.