Usually, hepatitis B surface antibodies of more than 1000 can be maintained for 10-12 years. Hepatitis B surface antibody level over 1000 indicates that the body has strong immunity against the hepatitis B virus, usually due to the stimulation of the body by the hepatitis B vaccination, which leads to a continuous increase in the level of antibody, but with the passage of time, the hepatitis B surface antibody in the body will continue to decrease. The hepatitis B virus will also continue to deplete the hepatitis B surface antibodies if one is exposed to it on a regular basis. When the Hepatitis B surface antibody test is negative, it is necessary to revaccinate with Hepatitis B vaccine to stimulate the body to produce Hepatitis B surface antibody. Hepatitis B vaccine recipients need to check the antibody level regularly, develop good living habits, regular work and rest, moderate exercise, maintain a good mood, eat foods rich in vitamins and proteins, and pay attention to hygiene, so as to improve the body’s immunity and prevent hepatitis B virus infection.