One of the most unfortunate situations in our clinical work is that children with brain injury syndrome miss the optimal treatment period. Some primary medical institutions and patients’ families lack the awareness of early diagnosis and treatment of brain injury syndrome, resulting in the child not getting the proper standardized treatment during the optimal treatment period, which is regrettable for the rest of his life. 1.What is brain injury syndrome? Brain injury syndrome refers to: in the mother’s pregnancy, birth or postnatal infancy, a variety of hazardous factors caused by the brain nerve tissue damage, causing abnormal clinical symptoms. These risk factors include high blood pressure, heart disease, diabetes mellitus, and viral infections during pregnancy, umbilical cord around the neck at birth, umbilical cord that is too thin or too short, placental abruption, placental aging, premature rupture of the water, contamination of the amniotic fluid, too much or too little amniotic fluid, malposition of the fetus (transverse fetus, breech fetus), preterm labor, premature delivery, excessive birth weight of more than 8 pounds, excessive birth weight of less than 5 pounds, and postnatal jaundice with a high and persistent jaundice index. Jaundice index is too high and prolonged, encephalitis, meningitis, intracranial hemorrhage due to coagulation disorders, etc. Children with the above risk factors may suffer from brain injury syndromes and must be followed up on a regular basis for early detection of problems. Specific clinical manifestations include the following: easily startled, easily startled by even the slightest sound. Poor mental performance, not opening eyes for several days after birth, and low milk intake. Abnormal grunting and straining. Pushing up, kicking and hitting the bed vigorously with arms and legs. Abnormal inward retraction of thumbs and excessive clenching of fists in both hands. Frequent spitting up. The above abnormalities are mostly early symptoms of Brain Injury Syndrome (BIS). Parents must pay attention to it. 2.What are the dangers of Brain Injury Syndrome? The above factors damage the brain tissue, different brain tissue functional area damage will have different performance, affect the motor area will appear cerebral palsy. Cerebral palsy is the most common sequel, that is, the damage to the motor area caused by the arm, leg movement disorders, can’t walk or walking posture is difficult to see. Affecting the intellectual center will result in mental retardation, affecting the language center will result in less pronunciation and difficulty in speaking, affecting the auditory center will result in hearing impairment, and the brain tissue of the visual center will result in blindness in both eyes. In other words, brain injury syndrome is the early stage of cerebral palsy and other diseases. If effectively treated, the child may be completely restored to normal; if not effectively treated, it may develop into cerebral palsy, intellectual and language disorders, and hearing and vision abnormalities. 3.Why should brain injury syndrome be diagnosed and treated early? The human brain has only two developmental peaks in a lifetime, i.e. during the mother’s pregnancy and within 1 year after birth. Currently, the mainstream view is that brain tissue damage in adulthood cannot be regenerated. Brain tissue develops rapidly during the mother’s pregnancy when the fertilized egg splits into an embryo. If any of the above mentioned risk factors poison the brain nerve tissue, it is easy to cause brain damage, and it is important to try to avoid poisoning by these factors. Another developmental peak of the brain tissue is within the first week of life, and the development in this period shows an inverted curve situation. That is, the fastest within 3 months, 3-6 months of rapid development, 6-12 months is okay, after 12 months of development slows down significantly. The head circumference of a child grows 2 centimeters per month in March, 1 centimeter in March-June, 0.5 centimeters in June-December, and only about 2 centimeters per year after 1 year of age, which is equivalent to the monthly development rate in March. Therefore, the treatment of brain injury emphasizes early treatment, to seize the golden period of brain development is most important, in these golden periods to give rehabilitation therapy, can promote the cerebral cortex excitation, repair damage lesions, prevent glial scar formation;; drugs through the blood-brain barrier, promote nerve cell development, promote the recovery of damaged neurophysiological function. 3 months called ultra-early treatment, the cure rate is up to 90%, 6 months called early treatment, cure rate of 60%, and 1 year of age, the cure rate of 60%. Within 3 months, it is called ultra-early treatment, with a cure rate of 90%, and within 6 months, it is called early treatment, with a cure rate of 60%. Therefore, children with the above mentioned risk factors and early manifestations should be treated early so as not to miss the treatment period. In the end, it costs more money and the treatment effect is not good.