Craniopharyngioma is a congenital tumor, accounting for about 5% of intracranial tumors, mostly seen in children and adolescents, and more in males than females. Craniopharyngioma is located in the saddle area and its growth presses on the adjacent pituitary gland, pituitary stalk and hypothalamus, causing dysfunction of these structures, which mainly manifests clinically as headache, mental indifference, visual and visual field disorders, water and electrolyte disorders (polydipsia and polyuria), poor appetite, weakness, dry and white skin with little sweating, short stature, obesity and delayed development of secondary sexual characteristics in children. Once diagnosed, all should be operated as soon as possible, striving for total or near-total resection, and postoperative adjuvant radiotherapy, which can make the child get long-term survival. If the child undergoes tumor resection under general anesthesia, postoperative care should be according to postoperative care under general anesthesia, continuous oxygenation, close observation of changes in condition, cardiac and electric vital signs monitoring, head elevation 30°, and detailed condition record. According to the routine care of operating area drainage and ventricular drainage, remove the operating area drainage tube in 48h, and the ventricular drainage tube in 3-5 days, and remove the stitches of the wound in 7-8 days. 2.Postoperative infusion Check the blood electrolytes according to the doctor’s prescription, and adjust the type and quantity of infusion according to the blood sodium, blood potassium and urine volume. During the infusion process, closely observe the changes in the condition to prevent the child from having epilepsy and coma when the blood sodium is too high or too low. If mild epilepsy occurs, luminal sodium 0.1gq8h can be administered intramuscularly. Generally, dexamethasone 5-10mg is routinely applied intravenously in fluids after surgery to prevent hypopituitarism resulting in decreased hormone levels and prevent laryngeal edema. 3, close monitoring of vital signs during care Postoperative children may have mild agitation, such as hallucinations, hallucinations and other psychiatric symptoms, should be placed in the monitoring room dedicated supervision, close observation of changes in vital signs, problems found in a timely manner. Keep the respiratory tract unobstructed. The child should be given intratracheal nebulized inhalation twice a day to prevent lung infection. 4, skin, oral care daily with warm water bath, turn on time, keep the bed sheet flat, clean, prevent the occurrence of bedsores. Apply lip oil on the lips to prevent dryness and cracking, and prevent blistering of the lips during postoperative fever. 5. Psychological and health guidance (1) The prognosis is better for those who take medication on time and in accordance with the dosage for total resection. As the surgery will produce a certain degree of damage to the hypothalamus, there will be endocrine changes for a long time after the surgery. For those who have urinary collapse, we should tell the children to take oral long-acting urinary collapse stop or mydriatic tablets and review them regularly. Sometimes children may also have obesity symptoms and need to take thyroxine and growth hormone. When children are close to puberty, they need to use sex hormones to promote the development of secondary sex characteristics. The use of various hormones as prescribed by the doctor can make the child’s figure and sex characteristics develop normally. (2) Maintain the child’s stable mood to illustrate the importance of maintaining a good and stable mood to promote health, and try to create a good recuperation environment during the recovery phase of the disease. (3) Strengthen the child’s nutrition. Due to the trauma of surgery, energy consumption is high, and the child is in the growth and development stage, a comprehensive diet should be given, and a diet with high protein, high calories, high vitamins and easy digestion should be strengthened to promote recovery. Because of the young age of the children, nursing staff should go deep into the ward often and care for the children with a gentle attitude and tone of voice according to the growth and development characteristics of adolescents and children.