When you think of gout, arthritis is the first thing that comes to mind. But what actually endangers work, life and especially life expectancy is not the attack of arthritis, but the damage to the main internal organs. According to a 2004 report by the China Center for Disease and Health Research, the number of people with hyperuricemia in China is currently as high as 120 million, including more than 75 million people with gout, and is growing at a rate of 4% per year. Gout has become the second most common metabolic disease in China, along with diabetes. When it comes to gout, people will first think of arthritis, but in fact, the crisis to life, work and especially affect the life expectancy is not because of the attack of arthritis, but the damage to the main internal organs, statistics, gout patients without regular treatment within five years, 50% of patients will be involved in the kidneys, leading to kidney function disorders, which is also the main cause of death in a number of years after the gout patients. The peak period of gout is between 30-45 years old When it comes to gout, many people take it for granted that it is a disease of the elderly, but in recent years, with the improvement of people’s living standards, the age of onset of gout has greatly advanced, said Professor Gou Jieruo, a large number of epidemiological surveys show that the peak period of onset of gout patients in China is between 30 and 45 years old, accounting for more than 1/3 of all gout patients. It is worth noting that in Guangdong, about 20% of people in health checkups are diagnosed with hyperuricemia or gout. It is understood that gout is due to the metabolic disorder of the body, making a large number of metabolites called “purine”. Purines can be converted into uric acid and excreted in the urine. However, when uric acid rises beyond the body’s ability to excrete it, hyperuricemia occurs. If hyperuricemia is not treated, uric acid accumulates in crystalline form and is deposited in many organs and tissues of the body, and if deposited in the joints, it can cause gout attacks. Deposits in the kidneys can cause renal insufficiency. Deposits in the urinary tract can cause urinary stones. There is also a correlation between hyperuricemia and myocardial infarction and cerebrovascular disease. What should a patient do if he/she has gout? Gout attacks are painful, and the area where gout attacks occur is usually red, swollen, and hot. For the treatment of gout, it must be divided into periods. In this case, it depends on what the gout patient’s past treatment background is like. In the past, if the treatment was very systematic and there were standardized uric acid-lowering drugs in the recent attacks, then we can continue to use the uric acid-lowering drug aid, plus very strong anti-inflammatory and painkilling drugs to relieve its acute The attack joint pain. However, if the patient did not use uric acid-lowering drugs before the attack, we do not advocate adding uric acid-lowering drugs during the acute attack, and only use anti-inflammatory and pain-relieving drugs to control the pain for one to two weeks, and then add uric acid-lowering drugs again after the arthritis attack improves. The second stage is the treatment in the intermittent and chronic phases, which we clinically classify as hepatogenic or nephrogenic according to the mechanism, with different medications. For example, if the main reason is liver, we will consider using drugs that inhibit liver enzymes to reduce uric acid synthesis to lower uric acid. It is worth noting that many patients are treated only in the first stage, but in fact the second stage of uric acid reduction is the most critical. Because this stage requires the use of uric acid-lowering drugs to control the uric acid level below 350 μmol/L, the treatment time is longer, during which the dosage should be adjusted under the guidance of the doctor, and the blood routine, liver and kidney function and other indicators should be reviewed regularly. Patients with high uric acid and gout should follow seven dietary control principles: 1. limit the intake of purine-containing foods to <150 mg of purine daily; 2. drink plenty of water, more than 2000 ml per day; 3. consume more alkaline plant foods, such as vegetables, fruits, etc.; 4. prefer protein sources containing low purine, such as milk, eggs, etc.; 5. adjust the diet and exercise intensity to maintain 6, obese people should lose weight, but do not seek rapid weight loss, because rapid weight loss can cause a large number of ketone body production, but inhibit uric acid excretion. 7, hyperlipidemia to limit the intake of fat.