Cold cycle microwave knife is an emerging means of tumor treatment, which is an improved treatment modality of traditional percutaneous puncture microwave coagulation therapy for tumors (PMCT) and belongs to minimally invasive interventional therapy. Through ultrasound or CT guidance, precise positioning, the microwave knife directly puncture to the tumor site, the polar molecules in the tissue under the action of microwave field high-speed movement, friction with each other to generate heat, in the tumor rapidly warming; when the temperature rises to about 60 degrees, the tumor cell protein denaturation and coagulation, resulting in irreversible necrosis, inhibition of the proliferation of tumor cells, and the same time, the impact on the surrounding normal tissues is very small, and low side effects. Low side effects. Cold cycle microwave knife has the advantages of image guidance, accurate positioning; minimally invasive, small damage to the patient, fast recovery; direct ablation of tumor cells, precise efficacy; high safety, etc. It is mainly used in the clinical treatment of liver cancer and other solid liver tumors.