Ketoacidosis caused by diabetes mellitus islet function is generally more difficult to recover, it is recommended that patients with diabetic ketoacidosis seek medical attention in a timely manner. Ketoacidosis is common in patients with type 1 diabetes, type 1 diabetes is caused by the destruction of pancreatic β-cells, insulin absolute insufficiency, and the destruction of pancreatic islet cells generally can not be regenerated. Ketoacidosis can also be seen in patients with type 2 diabetes mellitus. In the case of type 2 diabetes mellitus there is a possibility of recovery of insulin function, but there are a number of prerequisites for the recovery of insulin function and subsequent blood glucose monitoring is still required. The approach includes five areas: prevention, weight loss, intensive glucose lowering, metabolic surgery, and pancreas or islet transplantation. However, islet function remains more difficult to recover in most patients. Patients with ketoacidosis who have impaired islet function are advised to visit a hospital and consult a medical professional to see if there is any possibility of restoring islet function.