Gliomas are tumors that originate in the central nervous system. Gliomas are tumors that originate in the glial cells of the brain, and the pathogenesis is unknown. Two risk factors that have been identified are exposure to high doses of ionizing radiation and genetic mutations in genes with high epistasis associated with rare syndromes. In addition, carcinogenic factors such as nitrite foods, viral or bacterial infections may also be involved in the development of glioma. Various external causes lead to mutations or structural changes in some genes in the body that can lead to tumor development. There are some genes that cause tumor occurrence called oncogenes, and the abnormal activation of oncogenes leads to abnormal value-added of cells, which promotes the occurrence and development of tumor; there are also some genes that inhibit tumor, which we call oncogenes, and after mutation, the function of inhibiting tumor growth is lost, and the function of inhibiting tumor is lost, which also leads to the occurrence and development of tumor. In addition, the heritability of glioma is not clear for simple glioma, but there are some diseases with clear heritability, such as type II neurofibromatosis and tuberous sclerosis, which have clear heritability, and they often combine with glioma, in this case, if this type of patient has glioma, he may have heritability.