There are strict medical diagnostic criteria for depression. The depressive mood that inevitably occurs in everyone’s daily life is a normal phenomenon. Whether the degree of the disease is reached is professionally diagnosed, and only when this degree is reached is it called depression, not reached is just a depressed mood, which is very common. The diagnostic criteria of depression are based on the history of the disease, clinical symptoms, duration of the disease, as well as physical examination and laboratory tests, and the necessary exclusion criteria, and severity criteria, before the diagnosis can be made. The diagnostic criteria of depression are currently used more often in China is ICD-10, which is often used for the diagnosis of the first episode or relapse of depression, as well as the diagnosis of depressive episodes in double quite. The professional diagnostic criteria include: 1, the time criteria of depression, depressive manifestations should last for at least two consecutive weeks before it can be called depression; 2, exclusion criteria, the patient has no episodes in previous life that meet the criteria of mild mania or mania, nor is it due to psychoactive substances or organic mental disorders; 3, the patient’s core symptoms and additional symptoms should be combined together, the core symptoms include depressed mood, Loss of interest or lack of pleasure, low energy or excessive fatigue, and feeling particularly dull. Additional symptoms include loss of self-confidence and low self-esteem, unjustified self-blame or excessive and inappropriate guilt, recurrent thoughts of death or suicide, or suicidal behavior, reduced thinking or attention capacity, psychomotor changes, agitation or inhibition. Agitation is the love of temper, easy to get angry, mood, temper becomes large; 4, any type of sleep disorder, appetite changes, appetite changes are either reduced or increased, and weight changes accordingly.