A peptic ulcer is a well-defined, limited tissue loss involving the mucosa, submucosa, and muscular layer, and its formation is related to the digestion of gastric acid and pepsin, hence the name peptic ulcer. Since the ulcer mainly involves the stomach and duodenum, it is also called gastroduodenal ulcer. It is a common disease and multi-infection because of its long duration, persistence, high recurrence rate and many complications, which causes great physical and mental pain to patients and affects their quality of life. Therefore, in addition to effective drug treatment, good health education is extremely important to promote patients’ recovery, reduce recurrence and prevent complications. 1, peace of mind Peptic ulcer is the result of the role of psychological, physical and social aspects, of which psychological and social factors play an important role. If you have long-term mental tension, anxiety, mood swings are the reason for the formation or recurrence of ulcers. For friends with a stressful work life should learn mental regulation and self-relaxation techniques, such as learning to talk, deep breathing and participate in physically and mentally enjoyable group activities; develop good habits, regular diet, quit smoking and drinking, maintain an optimistic and calm mind, control their behavior and change their bad lifestyle. 2, dietary guidance ulcer bleeding period should be temporary fasting, to stop bleeding or only a small amount of bleeding can be into a light, easy to digest liquid food or soft food, a small number of meals, do not overeat or sleep after eating, do not eat too cold, too hot, spicy stimulating food, avoid sweet and easy to produce gas food, develop the habit of regular rationing, chew slowly. Eat more coarse grains, mixed grains, high fiber food. During the recovery period, it is not necessary to restrict the diet. If you have H. pylori (HP) infection, you should understand that HP is a key factor in the occurrence and recurrence of peptic ulcer, and fecal-oral transmission is an important means of transmission. You should share meals, do not share utensils with family members, do not eat raw vegetables and drink contaminated water, pay attention to personal hygiene, wash your hands carefully before and after meals, and develop good living hygiene habits. 4, medication guidance internal medicine is an important measure in the treatment of peptic ulcer. The method, time and precautions for taking medicine are particularly important. ①Taking time: gastric mucous membrane protective agents should be taken half an hour before meals, such as aluminum thioglycollate, colloidal bismuth, to reduce bile reflux, such as mosapride, domperidone also before meals; antacids should be taken 1h after meals; H2 receptor antagonists should be taken before meals or meals; cholinergic antagonists should be taken at bedtime. ②Caution: Colloidal bismuth agent works in acidic environment and cannot be taken with alkaline drugs; aluminum thioglycollate cannot be taken with multi-enzyme tablets; antacids should not be used with milk products and acidic food. Adverse reactions: bismuth is easy to cause constipation and black stool, which can disappear after stopping; Oak is easy to cause dizziness; cimetidine can cause liver and kidney damage, granulocyte deficiency, diarrhea and rash; cholinergic antagonist causes thirst and increased heart rate. ④Prohibited or cautious medications: indomethacin, aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs, as well as corticosteroids, reserpine, etc., because they can directly damage the gastric mucosa, stimulate increased gastric acid secretion and induce or aggravate the occurrence of ulcers. ⑤ Adhere to the medication after discharge and complete the course of treatment. Actively cooperate with treatment and care, and voluntarily establish a scientific and healthy lifestyle, so as to effectively prevent the recurrence of the disease.