What is transaminase

  Aminotransferases, also known as aminotransferases, are important catalysts in human metabolism. Aminotransferases are mainly found in human liver cells, and when liver cells become necrotic, as well as inflammatory and toxic, they can cause damage to liver cells, so aminotransferases are released into the blood in large amounts, causing an increase in serum aminotransferase activity.  By performing a transaminase test, it is possible to determine whether liver cells are damaged. The main tests used for liver function tests are alanine aminotransferase and aspartate aminotransferase. When hepatocytes are damaged, increased hepatocyte membrane permeability leads to elevated serum activity of both aminotransferases; in moderate hepatocyte damage, the leakage rate of alanine aminotransferase is greater than that of aspartate aminotransferase. Moreover, alanine aminotransferase assay is more sensitive than aspartate aminotransferase in responding to hepatocyte injury. In general, the activity of transaminase is elevated when viral hepatitis, alcoholic liver disease, fatty liver, liver cancer, and cirrhosis are present. In addition, aspartate aminotransferase is also increased when 6-8 hours after an acute myocardial infarction.  Transaminases are the most sensitive enzyme for determining liver damage. The degree of liver damage is determined by transaminases, as well as by reviewing transaminases to determine recovery from treatment by targeting treatment for diseases that cause elevated transaminases.