Early symptoms of scleroderma are skin lesions, or in the case of systemic scleroderma, Raynaud’s phenomenon, loss of appetite, joint pain, and irregular fever. According to whether the disease involves internal organs other than the skin, scleroderma can be divided into limited scleroderma and systemic scleroderma. Limited scleroderma mainly involves the skin, which can lead to skin edema, hardening, atrophy and other symptoms, and generally does not involve the internal organs; systemic scleroderma patients in addition to the skin is involved in the disease, but the disease also involves the internal organs and other organs, which can lead to corresponding symptoms. Early symptoms of systemic scleroderma include Raynaud’s phenomenon, in which the tips of the fingers and toes of the patients may become blue or pale due to emotional changes or cold, in addition to joint pain and loss of appetite. Scleroderma patients are advised to go to the rheumatology and immunology department of regular hospitals for detailed consultation and treatment as prescribed by the doctor.