There are many factors that trigger acne, including androgens in the body, excessive sebum secretion, hyperkeratosis of the epithelium at the mouth of the hair follicle, Propionibacterium acnes infection, and genetics, which are the result of a combination of factors. Under normal circumstances, the sebaceous glands in the skin secrete a certain amount of oil that overflows from the hair follicles to lubricate and protect the skin, and its secretion activities are regulated by androgens in the body. If the androgen level is too high, or if the epithelium of the hair follicle is abnormally keratinized and cannot shed normally, the follicle opening becomes smaller and sebum accumulates at the follicle opening to form acne. Skin oil, aging dead skin in the pores and bacterial retention can cause inflammation and pus formation. In addition, genetic factors directly affect the occurrence of acne, the distribution of skin damage and the duration of the disease. Other factors such as improper use of cosmetics that cause blockage of the hair follicles, endocrine disorders due to psychological factors, stimulation of spicy foods such as tobacco and alcohol, excessive consumption of sugar, fat, and pharmaceutical androgens, etc. can cause or aggravate acne.