Integrated treatment for hepatocellular carcinoma includes radical surgical resection and liver transplantation, transhepatic artery interventional chemoembolization, percutaneous alcohol or acetic acid injection, radiofrequency or microwave ablation therapy, radiation therapy, chemotherapy, molecular targeted drug therapy, etc. For each patient, the appropriate treatment modality and the sequential combination of different treatment methods must be selected depending on the liver function, the size, number, location, metastasis or not of the tumor, and the affordability of the patient. There are many complications to be considered in liver cancer treatment, and each patient needs to be treated by a multidisciplinary team including hepatobiliary surgery, gastroenterology, oncology, ultrasound, diagnostic radiology and interventional radiology. This is the trend of liver cancer treatment and the most reasonable and effective method.