1.What is hormone-dependent dermatitis? Hormone-dependent dermatitis is called corticosteroid-dependent dermatitis or glucocorticoid-dependent dermatitis, also referred to as hormonal dermatitis, which is a non-purulent inflammation of the skin caused by the patient’s long-term repeated use of improper or abusive topical corticosteroid preparations, causing the affected skin to become dependent on the drug, easily occurring in patients who improperly use glucocorticoid topical preparations for facial dermatosis, so it is also often It is often called facial hormone-dependent dermatitis. 2. What are the signs of hormone-dependent dermatitis? After using glucocorticosteroid topical preparations, the original disease improves rapidly, but cannot be cured; after treatment lasts for several weeks or months, once the drug is stopped, erythema, papules, tenderness, fissures, pustules, desquamation, pain, itching, burning, tightness, and deterioration of the original disease occur within 1 to 2 days; when topical hormones are used again, the above symptoms quickly subside, and if the drug is stopped again, rebound dermatitis occurs rapidly, and it is heavier than before. If discontinued, rebound dermatitis occurs rapidly and is more severe than before. To avoid the pain of rebound dermatitis after discontinuation, patients rely entirely on topical hormones. Some of the original topical preparations are not effective and must be replaced with stronger hormonal topical preparations, or increase the dosage, or shorten the interval between medications, in order to improve the symptoms, the amount of medication is proportional to the length of the disease, the longer the disease, the more medication, the heavier the condition. 3. Why is the proportion of women among hormone dependent dermatitis patients much greater than the proportion of men? This is because women care more about their “face” than men, and once they have discomfort on their face, they like to apply their own medicine in order to solve the problem quickly. Secondly, women prefer efficacious cosmetics to treat acne, pigmentation or sensitive skin, and many of these efficacious cosmetics have irregularly added hormone drugs. 4.What are the side effects of long-term topical use of hormones on the skin? When hormone creams are used on the face and pubic area for a long time, the side effects are relatively easy to occur because of the easy absorption of corticosteroids in these parts of the skin; it is easy to cause pigmentation, skin atrophy, rosacea-like dermatitis, acne-like dermatitis, skin laxity, severe capillary dilation (i.e. red blood), increased skin sensitivity, enlarged pores, increased and thickened body hair, hormone dependent dermatitis, etc. . Especially for infants and children, the skin is delicate and should not be used on a large scale for a long time. 5. Why do doctors use hormone creams when they have many side effects? Corticosteroids have anti-allergic effect of suppressing immune reaction, and can reduce congestion and edema after topical application, so that the degree of itching and inflammatory reaction of certain skin damage can be temporarily relieved and subside. 6.What are the common hormone creams on the market? Due to the publicity effect of manufacturers’ advertisements, the names of many hormone creams are not unfamiliar among the common people, such as Pikang Wang Cream, Dermatoplanin Cream, Skin Relaxation Cream, Compound Conalex Cream, Skin Cream, Skin Lotion, etc. Among them, Pikang Wang Cream contains the most potent preparation of Clobetasol, which also causes the highest proportion of side effects, these drugs are commonly used in dermatology and have different curative effects on a variety of skin diseases, but patients should not purchase them on their own. The dermatologist should strictly use the drugs under the guidance of the dermatologist. 7.What kind of skin atrophy or redness (capillary dilation) is likely to occur under the circumstances of hormone topical application? The duration of drug application is too long or the area of application is too large. 8.Why do some blemish creams or desensitizing cosmetics cause hormone dependent dermatitis? This is because short-term use of hormones has a whitening effect or anti-allergic effect on the skin, but long-term repeated use will cause skin and systemic damage and cause hormonal dermatitis. During the monitoring of cosmetic adverse reactions by the Ministry of Health, there were many cases of hormone-dependent dermatitis, such as erythema, papules, exudation, capillary dilation and pigmentation, in the skin of consumers who used cosmetics for skin beauty or so-called desensitization treatment in beauty salons after stopping using cosmetics. Some of the cosmetics were found to have hormone-like substances added illegally. 9.Why does hormonal dermatitis occur? The exact pathogenesis is not yet fully understood, but may be related to skin atrophy caused by corticosteroids. Skin atrophy leads to thinning of the stratum corneum, degeneration of the dermal papillae, and loss of the skin barrier against water loss, which rapidly causes dryness and inflammation. Skin dehydration may be the main cause of inflammation in normal or existing lesions. 10.How to reduce and stop hormones in the treatment of hormonal dermatitis? The question of how to treat hormone discontinuation in the treatment of hormonal dermatitis is a matter of wisdom and benevolence, generally speaking, there are three kinds of hormone discontinuation as follows: first, the patient’s strong hormones are replaced by weak hormones until they are discontinued, during which other non-hormonal drugs are used to assist the treatment, so that the skin can gradually adapt to the transition process; second, the concentration of the hormone creams used is gradually reduced, and the interval is extended to eventually Third, the topical use of hormonal creams should be completely stopped and replaced by non-hormonal creams. As for how to reduce and stop hormones for each specific patient, it depends on each person’s different condition and the dermatologist’s experience in using medication, following the regular hospital dermatologist’s medical advice to treat hormonal dermatitis is the right choice for patients. 11.What are the best topical drugs for treating hormone dependent dermatitis? Tacrolimus ointment and pimecrolimus cream are local immunomodulators, which are used to treat hormonal dermatitis with good effect both at home and abroad, and others include heparin sodium ointment, Xicifol cream, zinc boron cream, zinc oxide cream, and furnace glycolic lotion. When the skin is dry and astringent in the late stage of recovery, you can add non-stimulating and moisturizing skin care products, such as Avène, Richland and other medicinal products or Shanghai Bacitracin brand Vaseline moisturizer, etc. 12.Is there any medication for hormonal dermatitis that is used internally? For stubborn hormonal dermatitis or severe hormonal dermatitis, patients can take oral antihistamines, immune regulating drugs, Chinese herbal medicine and other drugs under the guidance of doctors. 13.What should I do for hormone-induced red blood cells (dilated capillaries)? Photorejuvenation and laser cosmetic instruments can be applied to treat it. 14.What are the contraindications and precautions for hormone dependent dermatitis? During the treatment period, it is advisable to eat light food and avoid some spicy and irritating food and alcohol. Due to the long treatment period of this disease, patients should maintain a good state of mind and not get angry and anxious. 15.How long does it take to cure hormonal dermatitis? It takes 2 months to 2 years to cure hormonal dermatitis, and the cure time is proportional to the strength and time of the hormone preparations applied topically; moreover, patients still have high skin sensitivity after the complete disappearance of facial lesions, so it takes longer to recover completely; at the same time, secondary hyperpigmentation and erythema (dilated capillaries) are also problems that exist after patients are cured. 16.How to prevent the occurrence of hormonal dermatitis? Patients with skin diseases, especially facial skin diseases, must use medication under the guidance of dermatologists in regular hospitals, rather than purchasing medication on their own or getting non-dermatologists to prescribe hormonal creams for a long time. Secondly, avoid self-use or use of efficacious cosmetics in beauty salons to avoid the harm of hormones that may be contained in them to unknowingly use the skin.