1. ① Children with precocious puberty of bone age first need to take orthopantomographs of the left hand to evaluate bone age and predict adult height in detail. The detailed assessment of bone age and prediction of adult height is very important for the selection of treatment plan, and knowing the approximate range of predicted height will help to select a more reasonable treatment plan; ②Secondly, sex hormone level (generally check sex hormone six) and breast ultrasound, gynecological ultrasound (observe the size of uterus, ovaries and follicles. If the patient is a boy, the testicular size can be checked) to determine the sexual development; ③Pituitary magnetic resonance imaging (MRI), because the pituitary gland is the endocrine center, especially if there is a suspicion of central precocious puberty, it is necessary to check the pituitary magnetic resonance imaging (MRI). Some children with precocious puberty also need to check AFP and HCG to exclude germ cell tumors, etc.; ④Check thyroid hormone level for thyroid function, which can also cause precocious puberty in hypothyroidism. The GnRH excitation test can be done without fasting or water, and the blood should be drawn 4 times with 2-3ml each time. 3. For those who do not consider applying GnRHa treatment for the time being for pseudo-precocious puberty, they can temporarily not do the GnRH excitation test. Do GnRH excitation test. If the excitation shows pseudosexuality, it does not mean that it is still pseudosexual after a few months, and the excitation needs to be repeated at a later stage, in order to reduce the child’s pain can be temporarily not done, but must be regularly re-examined, pseudoprematurity at any time there is the possibility of turning into true, and most of them will eventually turn into true, only the length of time, otherwise the child will not be able to develop. 4, late treatment can be based on the development of the child with GnRH (sex hormone releasing hormone) alone or GnRH and GH (growth hormone) combined treatment.