In general, the test for precocious puberty is based on Luteinizing Hormone (LH) in girls and Testosterone (T) in boys, with values exceeding normal levels indicating the possibility of precocious puberty.
Sex hormone 6 is only a basic screening test for children, and needs to be combined with other tests for a comprehensive diagnosis. The gonadotropin-releasing hormone test is the gold standard for diagnosis.
The 6 hormones in children generally include: follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), progesterone (P), and testosterone (T). In girls, the main focus is on Luteinizing Hormone (LH) and in boys, Testosterone (T).
1. Testosterone (T): It is a steroid hormone, secreted by the testes in men or the ovaries in women. Among the 6 sex hormones in children, the concentration of testosterone in the blood of male children is significantly higher than that of normal children of the same age, which represents the possibility of precocious puberty.
2. Luteinizing hormone (LH): It can promote the conversion of sex hormones into sex hormones in gonadal cells. Luteinizing hormone (LH) levels between 3.0 and 5.0 IU/L may indicate the presence of precocious puberty. If LH levels are >5.0 IU/L, the gonadal axis can be determined to be activated, and the diagnosis can be confirmed without the need for gonadotropin-releasing hormone stimulation testing.
If a child shows signs of precocious puberty, it is recommended that he or she be screened in a regular hospital and undergoes the relevant tests recommended by the physician, and the diagnosis should be interpreted by the attending physician.