You can get the cervical cancer vaccine without checking for HPV. In general, women without a history of sexual intercourse are less likely to be infected with HPV and have a better immune effect after cervical cancer vaccination. Women with a history of sexual intercourse have a relatively higher chance of HPV infection and weaker immune effect, but it is still recommended to actively pursue cervical cancer vaccination. Even if HPV infection is present, cervical cancer vaccination is recommended to prevent other types of HPV infection. According to the guidance recommendations mentioned in the Chinese Expert Consensus on Clinical Application of Human Papilloma Virus Vaccine, except for women with a history of severe allergies, those preparing for pregnancy, and those who are pregnant or breastfeeding, all women of appropriate age should receive cervical cancer vaccination in a timely manner, especially those in high-risk groups, which mainly include women with high-risk lifestyles, those with genetic factors, and those with HPV infection. Regardless of the group, HPV screening can be performed before and after cervical cancer vaccination, and any high-risk HVP virus infection can be actively treated. After vaccination, routine cervical cancer screening should still be conducted on time to minimize the incidence of cervical cancer, reduce the risk of the disease and improve women’s quality of life.