Couples who remain infertile for more than a year after marriage should look for the reasons for this. Both parties should not put the blame on each other, but should be examined at the same time according to the principle of putting the easy ones before the difficult ones. From the male infertility causes, although very intricate and complex, but from the three basic examination can also have a preliminary brow, the key is how to find clues. First, the medical history can be started from three aspects The first aspect of the past disease? In the past suffered from long-term high fever disease, suffered from tuberculosis, had mumps and affect the testicles, scrotal surgery may affect the testicles. Secondly, if you are impotent and can’t have normal sex, or if you seem to have normal sex but never ejaculate, then even the best quality semen can’t get into the vagina, so of course you can’t get pregnant. Thirdly are there any occupational and environmental factors that affect testicular function? Such as exposure to radiation, chemical work, workers engaged in high-temperature operations, after the treatment of anti-cancer drugs, patients who have taken certain hormones or long-term alcoholism and smoking, can destroy the spermatogenic function of the testicles and cause infertility. Second, physical examination focus on reproductive organs, body type and secondary sexual characteristics of the development of the body can reflect the situation of the body’s sex hormones, but the abnormalities of the reproductive organs is the key to infertility, such as the penis with or without deformities, testicular size, epididymis with or without hard knots and varicocele and other conditions, are important clues. Third, semen check whether the quality of normal semen can be divided into sperm and seminal plasma two parts, of which sperm is the key, seminal plasma is the secretion of the accessory sex glands, play a role in nutritional protection and transportation of sperm, both of which are very important for fertility. Semen routine usually includes eight indicators, namely semen volume, color, pH, viscosity, sperm density, activity rate, motility, malformation rate, etc. The eight indicators can suggest the quantity and quality of sperm, and also reveal the nature of seminal plasma, but of the eight, sperm density, viability, motility, and malformation rate are more important, and often serve as the basis for diagnosis and a reference to determine whether or not the disease can be cured. If the sperm count is less than 20 million per milliliter, the survival rate is less than 50%, the motility (less than 25% of A-grade sperm, less than 50% of A+B-grade sperm), and the abnormality rate is more than 70%, all of them should be considered as poor semen quality, which is called oligozoospermia, weak spermatozoospermia, and abnormal spermatozoospermia respectively, and of course, the other indexes are very important, such as semen volume is less than 1.5 milliliters, the acidity and alkalinity are less than 7.0 or higher than 8.0, and semen is still jelly-like for more than 60 minutes, which is also very important. remains jelly-like and not liquefied for more than 60 minutes can be the cause of male infertility. A combination of these three basic tests to analyze often leads to certain conclusions. If the patient’s secondary sex characteristics are underdeveloped, the testes are very small, and there are no spermatozoa in the semen tests, it is basically certain that the testes are underdeveloped. If there are no sperm in the semen, the testes are normal in size on examination, and the vas deferens cannot be detected or the vas deferens are thick and nodular, obstructive azoospermia may be present. If the sperm count is low and mobility is low, and physical examination reveals varicocele, then it is likely to be oligozoospermia caused by varicocele, and surgical treatment should be considered if medication fails to be effective. If you can only find some clues from the above examination but can not confirm the diagnosis, you should take further examination to confirm the diagnosis, such as accessory gland infection, anti-sperm antibodies, chromosomes, genes and other tests. Only by identifying the exact cause of the disease and carrying out targeted treatment, can we achieve the purpose of fertility, otherwise blindly taking medication or indiscriminate use of medication will be twice the result with half the effort.