China is a large country with hepatitis B, and a considerable number of patients have cirrhosis and liver cancer on top of it. Because of its fast growth rate and easy intrahepatic and extrahepatic metastasis, liver cancer is called the “king of cancers”, which seriously threatens the life and health of patients. In the past 10 years, with the application of hepatic resection surgery, local treatment (radiofrequency, anhydrous alcohol injection, etc.), interventional treatment and biological treatment, the efficacy of hepatocellular carcinoma has been significantly improved. However, due to the numerous treatment means for liver cancer and the fact that each patient’s systemic condition, liver function reserve and tumor specifics are very different, which complicates its treatment, different doctors may have different views and treatment plans. I would like to discuss my own treatment experience in liver cancer treatment with some specific clinical cases. 1.Surgical treatment Currently, the primary treatment for hepatocellular carcinoma is surgical resection, the prerequisite of which is that the patient has good general condition, can tolerate major surgery, good liver function reserve and no distant metastasis of tumor. Case 1: Patient Xu Moumou, male, 77 years old, was admitted to hospital with “epigastric discomfort for 2 weeks”. After admission, he was found to have normal liver function, AFP 620ng/, ICG 15min retention rate 7%; CT showed that the mass was located in the right hepatic segments VI and VII and some segments V and VIII, with a diameter of about 7.8cm, without intrahepatic subfoci and vascular infiltration; his general condition was good, without signs of distant metastasis. The right hemicolectomy was given, and now 1 year after the operation, the AFP was normal on reexamination, and CT showed no recurrence of tumor. The following picture shows the resected right hepatic tumor specimen. 2.Radiofrequency treatment General primary hepatocellular carcinoma or metastatic hepatocellular carcinoma with less than 5 liver tumors and maximum diameter less than 5cm, which cannot be surgically resected due to the following problems: poor general health; cirrhosis or liver insufficiency; recurrent hepatocellular carcinoma after surgery (relative indication). Case 2: Patient Qiao Moumou, male, 61 years old, was admitted to the hospital with “abdominal distension and jaundice for one month”. After admission, liver function TbiL 112umol/L, albumin 25g/L; AFP 228ng/L, ICG 15min retention rate 31%; CT showed a 4.7cm size mass in the left liver outer lobe, 3 masses of 1.8cm-2.2cm diameter in the right liver, no intrahepatic vascular infiltration, moderate amount of ascites; good general condition, no signs of distant tumor metastasis. After antiviral and liver protection treatment was given, liver function improved and ascites was reduced, radiofrequency treatment of liver masses was performed (2 times in total), and now 8 months after surgery, liver function TbiL 22umol/L, albumin 33g/LAFP was normal, and CT showed no tumor recurrence. In this regard, the patient made a video of his medical treatment in our department (you can watch it by typing “Sower of Hope Zhongnan Hospital” in the Baidu search). 3.Interventional treatment Generally, for those who have large tumors and are not suitable for surgical resection, and whose local treatment such as radiofrequency is not effective, hepatic artery embolization chemotherapy is suitable. For patients with hepatocellular carcinoma rupture and bleeding who are old and in poor general condition, or whose tumors are too large to be resected, priority is given to hepatic artery embolization to stop bleeding. Case 3: Patient Li Moumou, male, 82 years old, was admitted to the hospital as an emergency with “abdominal pain for 8 hours”. The patient also had coronary artery disease, atrial fibrillation and premature ventricular contractions. The patient was treated with emergency hepatic artery embolization and was discharged. He is now 1 year old and is surviving well.