1, because humans are not immune to syphilis, no preventive vaccine, therefore, the best prevention is to pay attention to sexual hygiene, cleanliness, abide by moral norms, strictly forbid promiscuity, avoid unclean sexual behavior. 2, in the early syphilis before the cure prohibited sex, female syphilis patients should avoid pregnancy before complete cure. 3, the sexual partners of syphilis patients should go to the hospital for examination and laboratory tests, and it is best to carry out treatment at the same time according to early syphilis. 4, the appearance of syphilis suspicious symptoms, should go to the regular hospital of venereal disease specialist, early diagnosis and treatment, once a clear diagnosis, need to fully cooperate with the doctor, thorough treatment. 5.After treatment of early syphilis, regular follow-up should be done for 2 to 3 years.